NPCDR

NPCDR provides molecular regulation data for natural product (NP)-based drug combinations to characterize regulated molecules, molecular pathways, and disease-specific mechanisms.

Key Features:

• Comprehensive Information: Includes NP-based drug combinations validated by clinical or experimental studies, covering diverse natural products and co-administered drugs.
• Disease-specific Molecular Regulation Data: Provides disease-specific annotations of molecules and molecular pathways regulated by NP-based combinations.
• Cross-referencing with External Databases: Cross-references NPs, drugs, regulated molecules, and pathways to external biological and pharmaceutical databases.

Scientific Applications:

• Network Pharmacology: Enables analysis of drug interaction networks involving natural products and their regulated targets and pathways.
• Medical Biochemistry: Supplies molecular regulation data to analyze biochemical interactions and molecular mechanisms in disease contexts.
• Medicinal Chemistry and Drug Design: Informs medicinal chemistry and drug design by providing regulated molecule and pathway data for NP-based combinations.

Methodology:

Curates NP-based drug combination entries validated by clinical or experimental studies and cross-references those entries to external biological and pharmaceutical databases.