NSDNA

NSDNA curates experimentally supported associations between noncoding RNAs (ncRNAs) and nervous system diseases (NSDs) to enable investigation of molecular mechanisms underlying NSDs.

Key Features:

• Dataset scope: 24,713 experimentally supported associations linking 8,593 ncRNAs and 1,429 nervous system diseases across 11 species, compiled from over 1,300 scientific articles.
• Evidence type: Associations are recorded with experimental support extracted from the primary literature.
• Organized interaction corpus: Aggregates and organizes ncRNA–NSD interactions to support analysis of functional and mechanistic relationships.

Scientific Applications:

• Molecular mechanism discovery: Facilitates investigation of ncRNA roles and molecular mechanisms in nervous system diseases.
• Comparative analyses: Enables cross-species comparison of ncRNA–NSD associations across 11 species.
• Hypothesis generation for therapeutics: Provides experimentally supported associations to inform target identification and experimental follow-up for potential therapeutic research.

Methodology:

Literature curation and compilation of experimentally supported ncRNA–NSD associations from over 1,300 scientific articles.