O-miner

O-miner performs comprehensive computational analysis and annotation of genomics and transcriptomics high-throughput profiling data from raw image files to extract biologically relevant insights.


Key Features:

  • End-to-End Analysis Workflow: Processing, normalization, statistical analysis, and functional annotation from raw input data for transcriptomic and genomic datasets.
  • Integration Capabilities: Handles large, heterogeneous datasets and overlays genomic and transcriptomic data with other biological and clinical data.
  • Analytical Suite: Provides tools for exploration and interpretation of complex datasets and for identification and prioritization of novel targets for further validation.
  • Knowledge Extraction: Correlates genomic and transcriptomic profiles with clinical data to support hypothesis generation and elucidation of underlying biological processes.

Scientific Applications:

  • Pathway and mechanism analysis: Building a comprehensive understanding of altered mechanisms and pathways within genomic and transcriptomic datasets.
  • Target prioritization and validation: Prioritizing novel targets from high-throughput data for subsequent experimental validation.
  • Multi-omics and clinical data integration: Integrating diverse biological and clinical datasets to investigate disease-relevant signatures and associations.
  • Genomics and transcriptomics studies: Supporting a wide range of applications across genomics and transcriptomics research involving complex and heterogeneous datasets.

Methodology:

Processing of raw image files, normalization, statistical analysis, functional annotation, and integration with biological databases, including correlation of genomic and transcriptomic profiles with clinical data.

Topics

Details

Tool Type:
web application
Operating Systems:
Linux, Windows, Mac
Added:
3/25/2017
Last Updated:
11/25/2024

Operations

Publications

Cutts RJ, Dayem Ullah AZ, Sangaralingam A, Gadaleta E, Lemoine NR, Chelala C. O-miner: an integrative platform for automated analysis and mining of -omics data. Nucleic Acids Research. 2012;40(W1):W560-W568. doi:10.1093/nar/gks432. PMID:22600742. PMCID:PMC3394300.

Documentation