OmicLoupe
OmicLoupe provides interactive exploration and visualization of omics datasets to identify technical limitations and biological trends across multiple studies and omics layers.
Key Features:
- Interactive Visualizations: More than 15 interactive cross-dataset visualizations for exploring and comparing gene product behavior across datasets, highlighting technical limitations and biological trends.
- Quality Control and Statistical Comparisons: Quality control assessments, statistical comparisons, overlap analyses, and correlation studies for dataset inspection and feature selection.
- Cross-Dataset Analysis: Comparative analysis across omics layers and datasets to identify consistent expression changes at transcript and protein levels.
- Rapid Exploration: Fast exploration of large-scale omics data using tailored visualizations that support comprehensive comparisons within and across data layers.
Scientific Applications:
- Multi-layer omics comparison: Detection of technical limitations and biological trends across omic layers, exemplified by identifying gene products with consistent expression changes in SARS-CoV-2 infection studies.
Methodology:
Uses tailored interactive visualizations together with quality control assessments, statistical comparisons, overlap analyses, correlation studies, and selection/export of features for downstream analysis.
Topics
Details
- License:
- MIT
- Tool Type:
- library
- Programming Languages:
- R
- Added:
- 10/25/2021
- Last Updated:
- 10/25/2021
Operations
Publications
Willforss J, Siino V, Levander F. OmicLoupe: facilitating biological discovery by interactive exploration of multiple omic datasets and statistical comparisons. BMC Bioinformatics. 2021;22(1). doi:10.1186/s12859-021-04043-5. PMID:33663372. PMCID:PMC7931979.
PMID: 33663372
PMCID: PMC7931979
Funding: - Stiftelsen för Miljöstrategisk Forskning: Mistra Biotech
- Lunds Tekniska Högskola, Lunds universitet: Proteoforms@LU
- Stiftelsen Olle Engkvist Byggmästare: 193-0623