OmicLoupe

OmicLoupe provides interactive exploration and visualization of omics datasets to identify technical limitations and biological trends across multiple studies and omics layers.


Key Features:

  • Interactive Visualizations: More than 15 interactive cross-dataset visualizations for exploring and comparing gene product behavior across datasets, highlighting technical limitations and biological trends.
  • Quality Control and Statistical Comparisons: Quality control assessments, statistical comparisons, overlap analyses, and correlation studies for dataset inspection and feature selection.
  • Cross-Dataset Analysis: Comparative analysis across omics layers and datasets to identify consistent expression changes at transcript and protein levels.
  • Rapid Exploration: Fast exploration of large-scale omics data using tailored visualizations that support comprehensive comparisons within and across data layers.

Scientific Applications:

  • Multi-layer omics comparison: Detection of technical limitations and biological trends across omic layers, exemplified by identifying gene products with consistent expression changes in SARS-CoV-2 infection studies.

Methodology:

Uses tailored interactive visualizations together with quality control assessments, statistical comparisons, overlap analyses, correlation studies, and selection/export of features for downstream analysis.

Topics

Details

License:
MIT
Tool Type:
library
Programming Languages:
R
Added:
10/25/2021
Last Updated:
10/25/2021

Operations

Publications

Willforss J, Siino V, Levander F. OmicLoupe: facilitating biological discovery by interactive exploration of multiple omic datasets and statistical comparisons. BMC Bioinformatics. 2021;22(1). doi:10.1186/s12859-021-04043-5. PMID:33663372. PMCID:PMC7931979.

PMID: 33663372
PMCID: PMC7931979
Funding: - Stiftelsen för Miljöstrategisk Forskning: Mistra Biotech - Lunds Tekniska Högskola, Lunds universitet: Proteoforms@LU - Stiftelsen Olle Engkvist Byggmästare: 193-0623

Links