OmicsView

OmicsView provides interactive visualization and analysis of NGS-derived expression omics datasets to enable exploration of transcriptional profiles across human tissues and diseases, including GTEx data.

Key Features:

• Comprehensive Data Integration: Preloaded with thousands of samples spanning numerous disease areas and normal tissue types, including the GTEx database.
• Harmonized Processing: All integrated datasets are processed using a harmonized pipeline to ensure consistency and reliability.
• Analytical Capabilities: Supports a wide range of analytical tasks for understanding disease pathology, identifying biomarkers, and evaluating the effects of interventions in vivo and in vitro, enabling rapid data mining of transcriptional signatures.
• Disease Case Study: Applied to Crohn’s disease datasets to identify key aspects of pathology, robust biomarkers, and markers indicative of treatment response.

Scientific Applications:

• Disease Pathology Exploration: Enables detailed analysis of gene expression profiles to elucidate molecular underpinnings of diseases.
• Biomarker Discovery: Supports identification of biomarkers for diagnosis, prognosis, and monitoring therapeutic responses.
• Interventional Studies: Facilitates assessment of intervention impacts on gene expression patterns in both in vivo and in vitro settings.

Methodology:

Integrated datasets, including NGS-derived expression data and GTEx, are processed using a harmonized pipeline.