OmicsVolcano

OmicsVolcano provides R-based visualization of high-throughput omics data using volcano plots to support identification and interpretation of differentially expressed genes and proteins and to highlight biologically relevant patterns such as mitochondrial pathways.


Key Features:

  • R implementation: Implemented in R for analysis and visualization of omics datasets.
  • Volcano plot generation: Generates volcano plots that display fold-change versus statistical significance.
  • Differential expression support: Supports identification and visualization of differentially expressed genes and proteins.
  • Pattern highlighting: Facilitates highlighting of biologically relevant patterns, including mitochondrial pathways.
  • High-throughput data handling: Designed to operate on large-scale omics datasets.
  • Image output: Produces high-quality graphical outputs suitable for figures and reports.

Scientific Applications:

  • Differential expression analysis: Identification and visualization of differentially expressed genes and proteins in omics experiments.
  • Pathway-focused visualization: Visualization and emphasis of pathway-level signals, including mitochondrial pathways.
  • Exploratory data analysis: Exploratory interpretation of large-scale omics datasets by mapping significance against fold-change.

Methodology:

Implemented in R and uses volcano plots to plot statistical significance versus fold-change for omics datasets.

Topics

Details

License:
GPL-3.0
Tool Type:
library
Programming Languages:
R
Added:
3/19/2021
Last Updated:
4/11/2021

Operations

Publications

Kuznetsova I, Lugmayr A, Rackham O, Filipovska A. OmicsVolcano: Software for intuitive visualization and interactive exploration of high-throughput biological data. STAR Protocols. 2021;2(1):100279. doi:10.1016/j.xpro.2020.100279. PMID:33532728. PMCID:PMC7821039.