OmicsVolcano
OmicsVolcano provides R-based visualization of high-throughput omics data using volcano plots to support identification and interpretation of differentially expressed genes and proteins and to highlight biologically relevant patterns such as mitochondrial pathways.
Key Features:
- R implementation: Implemented in R for analysis and visualization of omics datasets.
- Volcano plot generation: Generates volcano plots that display fold-change versus statistical significance.
- Differential expression support: Supports identification and visualization of differentially expressed genes and proteins.
- Pattern highlighting: Facilitates highlighting of biologically relevant patterns, including mitochondrial pathways.
- High-throughput data handling: Designed to operate on large-scale omics datasets.
- Image output: Produces high-quality graphical outputs suitable for figures and reports.
Scientific Applications:
- Differential expression analysis: Identification and visualization of differentially expressed genes and proteins in omics experiments.
- Pathway-focused visualization: Visualization and emphasis of pathway-level signals, including mitochondrial pathways.
- Exploratory data analysis: Exploratory interpretation of large-scale omics datasets by mapping significance against fold-change.
Methodology:
Implemented in R and uses volcano plots to plot statistical significance versus fold-change for omics datasets.
Topics
Details
- License:
- GPL-3.0
- Tool Type:
- library
- Programming Languages:
- R
- Added:
- 3/19/2021
- Last Updated:
- 4/11/2021
Operations
Publications
Kuznetsova I, Lugmayr A, Rackham O, Filipovska A. OmicsVolcano: Software for intuitive visualization and interactive exploration of high-throughput biological data. STAR Protocols. 2021;2(1):100279. doi:10.1016/j.xpro.2020.100279. PMID:33532728. PMCID:PMC7821039.