openCARP

openCARP simulates cardiac electrophysiology from single-cell ion channel dynamics to organ-level conduction to enable in-silico experiments in computational cardiology.

Key Features:

• Multi-Scale Simulation Capabilities: Supports simulations from single-cell ion channel dynamics to organ-level cardiac conduction.
• CARPutils Python Framework: Integrates the CARPutils Python framework to develop and automate simulation pipelines and experiment workflows.
• Pre- and Post-Processing Tools: Provides functions for data pre-processing, post-processing, and visualization of simulation results.

Scientific Applications:

• Cardiac electrophysiology research: Enables modeling and simulation of cardiac electrophysiology and heart function across biological scales.
• Atrial fibrillation studies: Facilitates multi-scale simulation of atrial fibrillation to investigate mechanisms and potential treatments.

Methodology:

Uses a structured modeling workflow for setting up and executing simulations, exemplified by multi-scale studies of atrial fibrillation.