OpenVariant

OpenVariant reads, parses, and operates on diverse input file formats including TSV, CSV, VCF, MAF, and BED, enabling customizable output structures for integration of variant data in cancer genomic analyses.

Key Features:

• Multi-format parsing: OpenVariant reads and parses TSV, CSV, VCF, MAF, and BED file formats.
• Customizable output structures: OpenVariant allows refinement of parsed data into customizable output structures within a single process.
• Extensible architecture: OpenVariant is an easily extendable Python package that facilitates seamless integration of variant data.

Scientific Applications:

• Cancer genomics: OpenVariant integrates variant data from diverse sources into cancer genomic analyses, addressing variability across databases and computational tools that annotate single nucleotide variants and indels identified through high-throughput DNA sequencing.

Methodology:

OpenVariant performs reading, parsing, and refinement of input file formats in a single process.