Orchestrating chromosome conformation capture analysis with Bioconductor

Orchestrating chromosome conformation capture analysis with Bioconductor provides data structures, computational methods, and visualization tools to investigate Hi-C, micro-C, and related 3C data in R.

Key Features:

• Data Structures: Provides specialized data structures for chromosome conformation capture data.
• Computational Methods: Implements computational methods for analyzing Hi-C, micro-C, and other 3C-related data.
• Visualization Tools: Includes visualization tools for chromosome conformation capture data.
• Workflow Integration: Supports integration of chromatin conformation capture data in multi-omics workflows.
• Data Processing: Enables processing and import of any type of chromosome conformation capture data.

Scientific Applications:

• 3D Genome Organization: Investigates the spatial organization of genomes through Hi-C, micro-C, and related assays.
• Multi-omics Integration: Facilitates integration of chromatin conformation data with other omics data types in comprehensive workflows.

Methodology:

The tool provides workflows to process, import, analyze, and visualize chromosome conformation capture data using R and Bioconductor.