OrganismDbi

OrganismDbi provides a unified programmatic interface to access and integrate genomic annotation resources across packages to enable consistent querying and manipulation of biological sequence annotations.


Key Features:

  • Unified Interface: Provides a consistent API for accessing annotation databases that have differing schemas.
  • Interoperability: Implements select methods common to annotation packages to enable cross-package interoperability.
  • Integration with Bioconductor: Distributed within the Bioconductor ecosystem and interoperable with over 934 packages for genomic and molecular biology analyses.
  • R-Based Framework: Operates within the R programming environment for statistical computing and graphics.

Scientific Applications:

  • Genome annotation consolidation: Integrating annotations from multiple sources to produce comprehensive biological sequence annotations.
  • High-throughput genomic analyses: Supplying standardized annotation access for large-scale genomic and molecular biology data analyses.
  • Cross-package comparative analyses: Enabling consistent application of methods across annotation packages for comparative and integrative studies.

Methodology:

The package implements select methods standardized across annotation packages to enable consistent querying and manipulation of annotation data and is subject to continuous automated testing.

Topics

Collections

Details

License:
Artistic-2.0
Tool Type:
command-line tool, library
Operating Systems:
Linux, Windows, Mac
Programming Languages:
R
Added:
1/17/2017
Last Updated:
11/25/2024

Operations

Publications

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M. Orchestrating high-throughput genomic analysis with Bioconductor. Nature Methods. 2015;12(2):115-121. doi:10.1038/nmeth.3252. PMID:25633503. PMCID:PMC4509590.

Documentation

Downloads