OrganismDbi
OrganismDbi provides a unified programmatic interface to access and integrate genomic annotation resources across packages to enable consistent querying and manipulation of biological sequence annotations.
Key Features:
- Unified Interface: Provides a consistent API for accessing annotation databases that have differing schemas.
- Interoperability: Implements select methods common to annotation packages to enable cross-package interoperability.
- Integration with Bioconductor: Distributed within the Bioconductor ecosystem and interoperable with over 934 packages for genomic and molecular biology analyses.
- R-Based Framework: Operates within the R programming environment for statistical computing and graphics.
Scientific Applications:
- Genome annotation consolidation: Integrating annotations from multiple sources to produce comprehensive biological sequence annotations.
- High-throughput genomic analyses: Supplying standardized annotation access for large-scale genomic and molecular biology data analyses.
- Cross-package comparative analyses: Enabling consistent application of methods across annotation packages for comparative and integrative studies.
Methodology:
The package implements select methods standardized across annotation packages to enable consistent querying and manipulation of annotation data and is subject to continuous automated testing.
Topics
Collections
Details
- License:
- Artistic-2.0
- Tool Type:
- command-line tool, library
- Operating Systems:
- Linux, Windows, Mac
- Programming Languages:
- R
- Added:
- 1/17/2017
- Last Updated:
- 11/25/2024
Operations
Publications
Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M. Orchestrating high-throughput genomic analysis with Bioconductor. Nature Methods. 2015;12(2):115-121. doi:10.1038/nmeth.3252. PMID:25633503. PMCID:PMC4509590.