OrthoSelect

OrthoSelect automates the identification of orthologous gene sequences from EST libraries and generates orthologous gene alignments, annotations, and gene-by-taxon data matrices for phylogenomic analyses.


Key Features:

  • Automated detection of orthologous gene sequences: Identifies orthologous gene sequences across different taxa from EST libraries.
  • Orthologous gene alignments: Generates and outputs alignments of orthologous genes for downstream evolutionary analyses.
  • Annotations and gene-by-taxon data matrices: Produces annotations and data matrices for each gene and taxon alongside the alignments.

Scientific Applications:

  • Phylogenetic Analysis: Uses orthologous gene alignments to infer evolutionary relationships among species.
  • Comparative Genomics: Facilitates identification of conserved genetic elements across taxa using ortholog sets and alignments.
  • Evolutionary Biology Research: Supports analyses of orthologous genes to investigate patterns and processes of biodiversity and evolution.

Methodology:

Automated identification of orthologous gene sequences from EST libraries and generation of orthologous gene alignments, annotations, and gene-by-taxon data matrices.

Topics

Details

Tool Type:
web application
Added:
2/14/2017
Last Updated:
11/25/2024

Operations

Publications

Schreiber F, Worheide G, Morgenstern B. OrthoSelect: a web server for selecting orthologous gene alignments from EST sequences. Nucleic Acids Research. 2009;37(Web Server):W185-W188. doi:10.1093/nar/gkp434. PMID:19491309. PMCID:PMC2703962.