Oxypred

Oxypred predicts oxygen-binding proteins and classifies them into six structural and functional classes using SVMs based on sequence composition to support protein function analysis and target identification.


Key Features:

  • Prediction of Oxygen-Binding Proteins: Oxypred uses SVM modules that utilize amino acid composition and dipeptide composition to predict oxygen-binding proteins, achieving maximum accuracies of 85.5% and 87.8% respectively.
  • Classification into Six Classes: The model categorizes oxygen-binding proteins into six distinct structural and functional classes to aid interpretation of their biological roles and interactions.
  • Five-Fold Cross-Validation: Model training and validation use five-fold cross-validation to assess generalizability and reduce overfitting.

Scientific Applications:

  • Biological Research: Facilitates study of protein function and interactions and supports identification of novel biomarkers for disease diagnosis.
  • Drug Discovery: Aids development of targeted therapies by identifying potential drug targets and enhances drug screening through accurate protein classification.
  • Environmental Studies: Contributes to understanding the role of oxygen-binding proteins in environmental adaptation and provides insights into the impact of environmental factors on protein function.

Methodology:

Uses SVM modules trained on amino acid composition and dipeptide composition with five-fold cross-validation.

Topics

Details

Tool Type:
web application
Operating Systems:
Linux, Windows, Mac
Programming Languages:
Perl
Added:
8/3/2017
Last Updated:
11/24/2024

Operations

Publications

Muthukrishnan S, Garg A, Raghava G. Oxypred: Prediction and Classification of Oxygen-Binding Proteins. Genomics, Proteomics & Bioinformatics. 2007;5(3-4):250-252. doi:10.1016/s1672-0229(08)60012-1. PMID:18267306. PMCID:PMC5054225.

Documentation

Links