Oxypred
Oxypred predicts oxygen-binding proteins and classifies them into six structural and functional classes using SVMs based on sequence composition to support protein function analysis and target identification.
Key Features:
- Prediction of Oxygen-Binding Proteins: Oxypred uses SVM modules that utilize amino acid composition and dipeptide composition to predict oxygen-binding proteins, achieving maximum accuracies of 85.5% and 87.8% respectively.
- Classification into Six Classes: The model categorizes oxygen-binding proteins into six distinct structural and functional classes to aid interpretation of their biological roles and interactions.
- Five-Fold Cross-Validation: Model training and validation use five-fold cross-validation to assess generalizability and reduce overfitting.
Scientific Applications:
- Biological Research: Facilitates study of protein function and interactions and supports identification of novel biomarkers for disease diagnosis.
- Drug Discovery: Aids development of targeted therapies by identifying potential drug targets and enhances drug screening through accurate protein classification.
- Environmental Studies: Contributes to understanding the role of oxygen-binding proteins in environmental adaptation and provides insights into the impact of environmental factors on protein function.
Methodology:
Uses SVM modules trained on amino acid composition and dipeptide composition with five-fold cross-validation.
Topics
Details
- Tool Type:
- web application
- Operating Systems:
- Linux, Windows, Mac
- Programming Languages:
- Perl
- Added:
- 8/3/2017
- Last Updated:
- 11/24/2024
Operations
Publications
Muthukrishnan S, Garg A, Raghava G. Oxypred: Prediction and Classification of Oxygen-Binding Proteins. Genomics, Proteomics & Bioinformatics. 2007;5(3-4):250-252. doi:10.1016/s1672-0229(08)60012-1. PMID:18267306. PMCID:PMC5054225.