Panomicon

Panomicon facilitates integrative analysis and visualization of multi-omics datasets with emphasis on mRNA and miRNA interaction networks.

Key Features:

• Multi-omics integration: Supports analysis of transcriptomics, genomics, proteomics and other omics data types for combined investigation of molecular profiles.
• Data storage and management: Provides storage and management capabilities for diverse omics datasets to support downstream analyses.
• Clustering and heatmap generation: Implements interactive clustering algorithms and heatmap generation for exploration of expression patterns.
• Interaction network visualization: Generates and visualizes interaction networks between omics data types, including miRNA–mRNA interaction networks.
• Provenance: Originates from the Toxygates platform developed for the Open TG-GATEs dataset.

Scientific Applications:

• Multi-omics disease research: Integration of multiple omics datasets to investigate complex diseases, exemplified by non-small cell lung cancer studies.
• miRNA–mRNA interaction analysis: Re-examination of miRNA–mRNA interaction networks to probe disease mechanisms and identify potential therapeutic targets.

Methodology:

Uses interactive clustering algorithms, heatmap generation, network visualization tools, and data storage/management to support multi-omics integration and exploration of miRNA and mRNA interactions.