Panorama

Panorama manages targeted proteomics data by ingesting Skyline documents, storing extracted results in a relational database schema, and supporting aggregation and export of chromatogram libraries for assay development and peak identification.

Key Features:

• Integration with Skyline: Enables publishing of Skyline documents to Panorama to capture experimental results from Skyline.
• Data Storage and Organization: Captures information from Skyline documents within a relational database schema to organize curated results and support fine-grained permissions.
• Collaboration and Data Sharing: Provides controlled data sharing with permission settings to enable collaborative research while maintaining data integrity.
• Data Aggregation and Export: Aggregates curated results and exports chromatogram libraries used by Skyline for target selection and validation of peptide peak identifications.

Scientific Applications:

• Targeted Proteomics Experiments: Facilitates design, execution, and analysis of targeted proteomics assays by providing curated quantitative results and chromatogram libraries.
• Data Validation and Optimization: Enables validation of peak identifications and optimization of target selection across experimental iterations using chromatogram libraries and curated results.
• Collaborative Research Projects: Supports multi-laboratory data sharing with permission controls to coordinate assay development and result curation.

Methodology:

Panorama ingests or receives published Skyline documents, captures extracted information into a relational database schema, aggregates curated results, exports chromatogram libraries, and enforces fine-grained permissions for data sharing.