paraCell

paraCell enables interactive analysis and visualization of standard and dual host-parasite single-cell RNA-seq data without requiring programming ability.

Key Features:

• Interactive Visualization: Provides tools for interactive analysis and visualization of pre-loaded single-cell data.
• Dual Host-Parasite Analysis: Supports analysis of both standard single-cell RNA-seq data and dual host-parasite single-cell RNA-seq data.
• Pre-loaded Dataset Access: Allows users to visualize and analyse pre-loaded single-cell data without programming ability.

Scientific Applications:

• Parasite Transcriptomics: Enables visualization and re-analysis of published Plasmodium and Trypanosoma single-cell transcriptomic datasets.
• Pathogen-Host Interaction Studies: Supports analysis of pathogen-host interactions using dual host-parasite datasets such as Toxoplasma-mouse and Theileria-cow scRNA-seq data.
• Disease Susceptibility Research: Facilitates investigation of host interferon-gamma response and gene expression profiles associated with disease susceptibility by intracellular parasites.

Methodology:

paraCell is built as an expansion of cellxgene_VIP.