parody

parody detects univariate and multivariate outliers in high-throughput genomic and molecular biology datasets using parametric statistical models and resistant statistics.


Key Features:

  • Univariate and Multivariate Outlier Detection: Performs both univariate and multivariate outlier detection to identify anomalous observations in datasets.
  • Parametric Methods: Implements parametric statistical models that assume specific distributions for structured outlier identification.
  • Resistant Statistics Support: Incorporates resistant statistical techniques that are robust to deviations from model assumptions and data anomalies.

Scientific Applications:

  • High-throughput Genomic Data QC: Detects outliers in high-throughput genomic datasets to support data quality control.
  • Differential Expression Studies: Identifies anomalous observations that can affect differential expression analyses.
  • Genome-wide Association Studies (GWAS): Flags outliers in GWAS datasets that could bias association results.
  • Molecular Biology Investigations: Supports molecular biology experiments by identifying anomalous measurements in experimental datasets.

Methodology:

Performs univariate and multivariate outlier detection using parametric statistical models and resistant-statistics-based techniques.

Topics

Collections

Details

License:
Artistic-2.0
Tool Type:
command-line tool, library
Operating Systems:
Linux, Windows, Mac
Programming Languages:
R
Added:
1/17/2017
Last Updated:
11/25/2024

Operations

Publications

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M. Orchestrating high-throughput genomic analysis with Bioconductor. Nature Methods. 2015;12(2):115-121. doi:10.1038/nmeth.3252. PMID:25633503. PMCID:PMC4509590.

Documentation

Downloads