pathRender

pathRender renders biological pathways as graph representations to visualize and interpret pathway data from pathway databases using Rgraphviz within the Bioconductor/R environment.


Key Features:

  • Graph Construction: Constructs graph representations of biological pathways by integrating data from established pathway databases.
  • Pathway Database Integration: Accepts and derives pathway information from pathway databases for graph generation.
  • Visualization with Rgraphviz: Uses the Rgraphviz package in R for graph layout and rendering of pathway networks.
  • Bioconductor Integration: Operates within the Bioconductor framework to leverage Bioconductor package infrastructure.
  • R Implementation: Implemented in the R programming language.

Scientific Applications:

  • Genomics and Molecular Biology: Supports visualization of pathway data in genomics and molecular biology studies.
  • Data Analysis and Interpretation: Facilitates interpretation of high-throughput genomic data by translating pathway information into graph representations.
  • Visualization of Biological Networks: Enables visualization of complex biological networks and relationships within pathway data.
  • Interdisciplinary Research: Provides pathway visualizations that can be used across collaborative, cross-disciplinary studies.

Methodology:

Constructs graphs from pathway database-derived data and renders them using Rgraphviz in R, operating within the Bioconductor framework to enable interoperability with other Bioconductor packages.

Topics

Collections

Details

License:
GPL-3.0
Tool Type:
command-line tool, library
Operating Systems:
Linux, Windows, Mac
Programming Languages:
R
Added:
1/17/2017
Last Updated:
11/25/2024

Operations

Publications

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M. Orchestrating high-throughput genomic analysis with Bioconductor. Nature Methods. 2015;12(2):115-121. doi:10.1038/nmeth.3252. PMID:25633503. PMCID:PMC4509590.

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