PatScanUI
PatScanUI performs exploratory pattern searches in biological sequences by applying user-defined PatScan patterns to identify sequence motifs and features relevant to genomics, proteomics, secondary metabolite, and drug discovery research.
Key Features:
- Exploratory pattern search: Supports discovery of novel or ill-defined sequence patterns by enabling searches when target motifs are not predefined.
- Generic PatScan pattern matching: Uses PatScan's pattern language and matching capabilities to detect complex sequence patterns and motifs.
- User-defined pattern construction and application: Accepts user-specified PatScan pattern specifications and applies them to biological sequence data for targeted searches.
Scientific Applications:
- Secondary metabolite discovery: Identification of sequence motifs and patterns associated with biosynthetic gene clusters and secondary metabolite pathways.
- Genomics: Detection of nucleotide sequence motifs relevant to gene regulation, structural elements, or evolutionary studies.
- Proteomics: Identification of amino acid sequence patterns and motifs relevant to protein function or post-translational modification sites.
- Drug discovery: Discovery of sequence features that may inform target identification, mechanism elucidation, or biomarker selection.
Methodology:
Construct user-defined PatScan pattern specifications and apply PatScan pattern-matching to biological sequences to identify matching motifs and relevant features.
Topics
Details
- License:
- AGPL-3.0
- Tool Type:
- web application
- Programming Languages:
- JavaScript, Python
- Added:
- 7/6/2018
- Last Updated:
- 11/25/2024
Operations
Publications
Blin K, Wohlleben W, Weber T. Patscanui: an intuitive web interface for searching patterns in DNA and protein data. Nucleic Acids Research. 2018;46(W1):W205-W208. doi:10.1093/nar/gky321. PMID:29722870. PMCID:PMC6030941.
DOI: 10.1093/nar/gky321
PMID: 29722870
PMCID: PMC6030941
Funding: - Novo Nordisk: NNF10CC1016517, NNF16OC0021746
- German Ministry of Education and Research: 0315585A