PepServe

PepServe analyzes peptide sequences and functional attributes to characterize peptide features and support studies such as protein identification, biomarker discovery, bioactivity investigation, and immune response analysis.


Key Features:

  • Feature Analysis: Analyzes peptides by sequence and functional attributes, including peptide fragments of proteins and naturally occurring peptides.
  • Clustering: Clusters peptides based on shared features to identify patterns and relationships within peptide datasets.
  • Visualization Tools: Generates graphical visualizations of peptide feature distributions and clustering results to aid interpretation.

Scientific Applications:

  • Protein Identification: Identifies proteins of origin from peptide sequence information.
  • Biomarker Discovery: Detects peptide features that correlate with biological conditions or diseases for potential biomarker identification.
  • Bioactivity Studies: Evaluates bioactive properties of peptides, their molecular interactions, and potential therapeutic applications.
  • Immune Response Analysis: Analyzes peptides involved in immunogenic processes to support immune response studies.

Methodology:

Processes peptide lists by applying algorithms that analyze sequence and functional features, clusters peptides based on their characteristics, and outputs visualizations of the results.

Topics

Collections

Details

Tool Type:
web application
Operating Systems:
Linux, Windows, Mac
Added:
2/14/2017
Last Updated:
11/25/2024

Operations

Data Inputs & Outputs

Clustering

Inputs

Outputs

    Publications

    Alexandridou A, Dovrolis N, Tsangaris GT, Nikita K, Spyrou G. PepServe: a web server for peptide analysis, clustering and visualization. Nucleic Acids Research. 2011;39(suppl):W381-W384. doi:10.1093/nar/gkr318. PMID:21572105. PMCID:PMC3125752.

    Documentation