pepstats (EBI)

pepstats (EBI) computes statistics of protein sequences and properties to support sequence-based protein characterization and integration with EMBL-EBI data resources.


Key Features:

  • Protein property statistics: Calculates numerical statistics for protein sequences and properties derived from input amino acid sequences.
  • Sequence analysis capabilities: Supports a broad spectrum of sequence analyses leveraging established bioinformatics applications.
  • Integration with EMBL-EBI resources: Connects to UniProt, InterPro, ENA, and Ensembl Genomes for linked data retrieval and annotation.
  • API access: Provides RESTful and SOAP-based APIs for programmatic submission and retrieval of results.
  • EMBL-EBI Job Dispatcher framework: Operates within the EMBL-EBI Job Dispatcher framework to access core analytical tools and data resources.
  • Data visualization for interpretation: Produces visual outputs to aid interpretation of computed protein statistics and complex data sets.

Scientific Applications:

  • Protein characterization: Generates quantitative descriptors of proteins to inform studies of structure, function, and interactions.
  • Genomics and proteomics data integration: Facilitates combined analyses using sequence-derived statistics linked to UniProt, InterPro, ENA, and Ensembl Genomes data.

Methodology:

Implements computations within the EMBL-EBI Job Dispatcher framework and exposes RESTful and SOAP APIs to access and process sequence data retrieved from UniProt, InterPro, ENA, and Ensembl Genomes.

Topics

Collections

Details

Tool Type:
api, web application
Operating Systems:
Linux, Windows, Mac
Added:
1/29/2015
Last Updated:
11/24/2024

Operations

Data Inputs & Outputs

Protein property calculation

Outputs

    Publications

    Madeira F, Pearce M, Tivey ARN, Basutkar P, Lee J, Edbali O, Madhusoodanan N, Kolesnikov A, Lopez R. Search and sequence analysis tools services from EMBL-EBI in 2022. Nucleic Acids Research. 2022;50(W1):W276-W279. doi:10.1093/nar/gkac240. PMID:35412617. PMCID:PMC9252731.

    PMID: 35412617
    PMCID: PMC9252731
    Funding: - EMBL-EBI: 824087 - BY-COVID: 101046203 - EarlyCause: 848158

    Rice P, Longden I, Bleasby A. EMBOSS: The European Molecular Biology Open Software Suite. Trends in Genetics. 2000;16(6):276-277. doi:10.1016/s0168-9525(00)02024-2.

    Madeira F, Madhusoodanan N, Lee J, Eusebi A, Niewielska A, Tivey ARN, Lopez R, Butcher S. The EMBL-EBI Job Dispatcher sequence analysis tools framework in 2024. Nucleic Acids Research. 2024;52(W1):W521-W525. doi:10.1093/nar/gkae241. PMID:38597606. PMCID:PMC11223882.

    Documentation

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    Related Tools

    pepstats
    Relation: uses