PERSEUS

PERSEUS visualizes pedigrees as directed graph networks using a force-repulsion layout to explore genetic relationships among accessions and to trace phenotypic traits to ancestral donors.


Key Features:

  • Directed graph pedigree representation: Pedigrees are represented as directed graph networks with nodes corresponding to individuals or accessions.
  • Force-repulsion layout: A force-repulsion method is used to distribute nodes in the network for clearer visualization of relationships.
  • Trait search and export: Phenotypic traits can be searched along pedigrees and exported for downstream analysis.
  • Trait tracing to ancestors: The system supports tracing phenotypic traits back to ancestral donors within the pedigree graph.
  • Support for genomic selection and prediction analyses: Visualizations and trait data are provided to aid genomic selection and prediction workflows.
  • Applicability to accessions and germplasm collections: Designed to represent and analyze relationships among accessions in breeding programs and germplasm collections.

Scientific Applications:

  • Breeding program analysis: Exploration of pedigree relationships and trait inheritance to inform selection decisions in breeding programs.
  • Germplasm curation and management: Analysis of lineage and trait provenance within germplasm collections and accession catalogs.
  • Evolutionary and genealogy studies: Investigation of genealogical relationships and lineage histories among related individuals or species.
  • Genotypic and phenotypic diversity analysis: Assessment of diversity patterns across accessions using pedigree and trait information.
  • Trait provenance and donor identification: Identification of ancestral donors contributing specific phenotypic traits.

Methodology:

Pedigrees are represented as directed graph networks with nodes as individuals and laid out using a force-repulsion algorithm; interactive network exploration and trait search/export functionality are provided.

Topics

Details

Cost:
Free of charge
Tool Type:
web application
Operating Systems:
Mac, Linux, Windows
Programming Languages:
JavaScript
Added:
5/24/2024
Last Updated:
11/24/2024

Operations

Publications

Pradas N, Jurado-Ruiz F, Onielfa C, Arús P, Aranzana MJ. <i>PERSEUS:</i> an interactive and intuitive web-based tool for pedigree visualization. Bioinformatics. 2024;40(2). doi:10.1093/bioinformatics/btae060. PMID:38310342. PMCID:PMC10898331.

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