PeruNPDB

PeruNPDB provides a curated database of 280 natural products from Peruvian flora and fauna to support chemoinformatics analyses and early-stage drug discovery.

Key Features:

• Extensive Collection: The initial release contains 280 natural compounds, approximately 95% originating from plants and 5% from animals.
• Chemoinformatic Evaluation: Includes detailed assessments of chemical space coverage, physicochemical properties, and overall chemical diversity.

Scientific Applications:

• Drug Discovery: Supports virtual screening campaigns and early-stage identification of potential therapeutic agents against biological targets.
• Biodiversity and Ethnopharmacology: Serves as a resource for studying Peru's megadiversity, endemic species, and ethnopharmacological practices.
• Comparative Studies: Enables comparison of Peruvian natural products with collections from Mexico, Brazil, India, and China to assess global natural product diversity.

Methodology:

Assembly and curation involved data collection and validation, followed by evaluation of chemical space coverage and physicochemical properties.