PETAL
PETAL analyzes biological pathways to detect long-distance crosstalk mechanisms and reveal critical nodes and interactions within pathway networks.
Key Features:
- Long-distance crosstalk detection: Identifies long-distance crosstalk mechanisms within biological pathway networks.
- Comprehensive pathway analysis: Performs comprehensive analyses to map interactions across pathways.
- Exhaustive automated search: Automates an exhaustive search within pathways to detect critical nodes and interactions without manual intervention.
- Implementation: Implemented in Python 3.
Scientific Applications:
- Therapeutic target and biomarker discovery: Aids in identifying novel therapeutic targets and biomarkers hidden within complex pathway networks.
- Drug development and disease strategy: Supports identification of pathway-based avenues for drug development and disease treatment strategies.
- Pathway interaction mapping: Reveals hidden connections and maps pathway interactions relevant to disease mechanisms.
Methodology:
Automates an exhaustive search within pathways to detect critical nodes and interactions; implemented in Python 3.
Topics
Details
- Programming Languages:
- Python
- Added:
- 1/18/2021
- Last Updated:
- 1/23/2021
Operations
Publications
Sgroi G, Russo G, Pappalardo F. PETAL: a Python tool for deep analysis of biological pathways. Bioinformatics. 2020;36(22-23):5553-5555. doi:10.1093/bioinformatics/btaa1032. PMID:33325491.
PMID: 33325491