PGV
PGV visualizes reference-agnostic pan-genomes to represent and enable exploration of genes and non-coding sequences across cultivars, accessions, or strains within a species.
Key Features:
- Reference-Agnostic Representation: Represents pan-genomes without reliance on a single reference genome, capturing genes and non-coding sequences present across individuals.
- Consensus Ordering: Organizes genomic data using consensus ordering to facilitate comparison and the identification of structural variations.
- Interactive Visualization: Provides interactive visualization capabilities for exploring pan-genomic variation and relationships among genomes.
Scientific Applications:
- Comparative Genomics: Enables comparison of genomic content and structure across multiple genomes within a species without a reference.
- Evolutionary Biology: Supports analysis of genomic diversity and structural variation for evolutionary inference.
- Plant Breeding and Diversity Studies: Facilitates visualization of pan-genomic variation across cultivars, accessions, or strains to inform studies of genetic diversity.
Methodology:
Implements a reference-agnostic representation of pan-genomes and organizes genomic sequences using consensus ordering for visualization and comparison.
Topics
Details
- License:
- MIT
- Cost:
- Free of charge
- Tool Type:
- command-line tool
- Operating Systems:
- Mac, Linux, Windows
- Programming Languages:
- Python
- Added:
- 4/9/2022
- Last Updated:
- 4/9/2022
Operations
Publications
Liang Q, Lonardi S. Reference-agnostic representation and visualization of pan-genomes. BMC Bioinformatics. 2021;22(1). doi:10.1186/s12859-021-04424-w. PMID:34656081. PMCID:PMC8520301.