Phenonaut

Phenonaut integrates multiomics datasets including high-content imaging, proteomics, and metabolomics to enable exploration of phenotypic spaces.


Key Features:

  • Data Workflow Management: Provides migration, control, integration, and auditability for multiomics datasets across acquisition to analysis.
  • Workflow Creation: Supports creation of workflows that are agnostic to data source and structure.
  • Data-Centric Transforms and Measures: Enables comprehensive dataset description and application of generic or specialized transforms and measures.
  • Python-based Implementation: Delivered as a Python package for programmatic construction and execution of analysis workflows.
  • Modular Architecture and Interoperability: Employs a modular design that ensures compatibility with a wide range of omics datasets and promotes reproducibility.

Scientific Applications:

  • Multiomics Integration: Facilitates combining high-content imaging, proteomics, and metabolomics data for integrated analyses.
  • Phenotypic Space Exploration: Enables exploration of phenotypic spaces across diverse omics platforms.
  • Holistic Molecular Characterization: Supports studies that require a comprehensive view of the molecular underpinnings of biological systems.

Methodology:

Uses a modular approach to data integration that allows construction and customization of workflows and ensures compatibility with a wide range of omics datasets to promote interoperability and reproducibility.

Topics

Details

License:
Apache-2.0
Cost:
Free of charge
Tool Type:
library
Operating Systems:
Mac, Linux, Windows
Programming Languages:
Python
Added:
11/7/2023
Last Updated:
11/24/2024

Operations

Publications

Shave S, Dawson JC, Athar AM, Nguyen CQ, Kasprowicz R, Carragher NO. Phenonaut: multiomics data integration for phenotypic space exploration. Bioinformatics. 2023;39(4). doi:10.1093/bioinformatics/btad143. PMID:36944259. PMCID:PMC10068743.

Documentation

Links