PhylochipAnalyzer

PhylochipAnalyzer analyzes hierarchical probe-set experiments by defining probe hierarchies and interpreting intensity data from hybridized chips to support phylogenetic relationship analysis.

Key Features:

• Interactive Hierarchy Definition: Enables interactive establishment of a hierarchy of probes for tailored hierarchical probe-set analysis.
• Data Analysis Mode: Loads and analyzes intensity data from hybridized chips according to predefined probe hierarchies.
• Export Capabilities: Exports hierarchical trees in Newick format and analyzed data to Excel.
• Configurability via Delphi Script: Includes a Delphi script to configure criteria for positive signals.

Scientific Applications:

• Phylogenetic analysis: Supports high-resolution phylogenetic analysis using hierarchical probe-sets derived from hybridization experiments.
• Microbial ecology and evolutionary biology: Facilitates studies of microbial diversity and evolutionary patterns through hierarchical probe-set interpretation.

Methodology:

Operation comprises two modes: interactive definition of probe hierarchies and analysis of hybridized chip intensity data according to the defined hierarchy.