PhyloMAd

PhyloMAd assesses the adequacy of phylogenetic models by evaluating models of nucleotide substitution and among-lineage rate variation using a fast likelihood-based method to support accurate statistical phylogenetic inference from large multi-locus phylogenomic datasets.

Key Features:

• Model Adequacy Assessment: Assesses the absolute adequacy of commonly used models of nucleotide substitution and among-lineage rate variation.
• Likelihood-Based Methodology: Uses a fast likelihood-based method to evaluate model adequacy.
• Multi-locus Dataset Handling: Scales to large multi-locus datasets for phylogenomic analyses.
• Relevance to Statistical Inference: Provides adequacy assessments pertinent to the accuracy of statistical phylogenetic inference.

Scientific Applications:

• Model selection and improvement: Informs selection and improvement of nucleotide substitution and among-lineage rate variation models.
• Phylogenomic analyses: Evaluates model adequacy in large multi-locus phylogenomic datasets to support downstream phylogenetic analyses.
• Enhancing inference accuracy: Helps identify inadequate models to improve the robustness of evolutionary inferences.

Methodology:

Performs fast likelihood-based evaluation of model adequacy for models of nucleotide substitution and among-lineage rate variation on multi-locus datasets.