piRNAdb

piRNAdb catalogs piwi-interacting RNAs (piRNAs) and associated annotations to support analysis of their genomic locations, clustering, and putative targets including genes and transposable elements.

Key Features:

• Extensive Data Collection: Catalogues 27,329 piRNAs derived from four human RNA-sequencing datasets and annotates 23,380 putative target genes and 47,060 associated gene ontology terms.
• Genomic Annotation: Provides genomic locations, clustering information, and potential targets on known genes and transposable elements for catalogued piRNAs.
• Cross-Database References: Provides direct links to other databases to connect piRNA entries with external annotations.
• Data Visualization and Integration: Implements data visualization and integration of multiple data types to aid analysis and interpretation of piRNA-related information.

Scientific Applications:

• Research Facilitation: Supports study of piRNA regulatory roles in gene expression and transposable element control.
• Data Integration: Enables linking of piRNA sequences to genomic locations, putative target genes, and gene ontology terms for multifaceted analyses.

Methodology:

piRNAdb compiles piRNAs identified from four human RNA-sequencing datasets and associates them with genomic coordinates, clusters, putative targets, and gene ontology annotations.