PLAN2L

PLAN2L performs literature mining and information extraction to retrieve and organize Arabidopsis thaliana biological data relevant to genetic, cellular, and molecular research.


Key Features:

  • Integration of Text Mining and Information Extraction: Uses text mining and information extraction to extract biological information from literature and complement existing annotation databases and bioinformatics-generated data.
  • Comprehensive Biological Topic Coverage: Retrieves information on protein interactions, gene regulation, sub-cellular localization, and processes including the cell cycle, flowering, root, leaf, and seed development in Arabidopsis thaliana.
  • Entity Pair Queries: Accepts predefined pairs of entities and returns literature-derived relationships together with supporting textual evidence.

Scientific Applications:

  • Hypothesis Generation: Exposes literature-derived relationships among genes, proteins, and processes in Arabidopsis thaliana to support formulation of hypotheses.
  • Experimental Design: Provides extracted evidence on gene regulation, interactions, and sub-cellular localization to inform experimental planning.
  • Model Validation and Network Analysis: Facilitates validation of biological models and analysis of gene regulatory and interaction networks using curated literature evidence.

Methodology:

Applies text mining to scan published research and information extraction to identify and organize relationships and contextual textual evidence related to Arabidopsis thaliana.

Topics

Details

Tool Type:
web application
Operating Systems:
Linux, Windows, Mac
Programming Languages:
Perl, Python, C
Added:
3/24/2017
Last Updated:
11/25/2024

Operations

Publications

Krallinger M, Rodriguez-Penagos C, Tendulkar A, Valencia A. PLAN2L: a web tool for integrated text mining and literature-based bioentity relation extraction. Nucleic Acids Research. 2009;37(Web Server):W160-W165. doi:10.1093/nar/gkp484. PMID:19520768. PMCID:PMC2703909.

Documentation