PLANA

PLANA provides a controlled anatomy ontology for Schmidtea mediterranea that organizes and annotates anatomical structures across developmental stages and in intact and regenerating body fragments to support interoperability and gene-expression mapping.

Key Features:

• Comprehensive Anatomical Terms: Contains over 850 defined terms describing S. mediterranea anatomy from subcellular structures to whole systems across life cycle stages and both intact animals and regenerating body fragments.
• Interoperability and Integration: Incorporates terms from other established anatomy ontologies to enable cross-platform and cross-species searchability and comparative anatomy analyses.
• Data Curation Resources: Supports creation of a staging series for planarian embryogenesis and a molecular fate-mapping atlas and underpins the Planarian Anatomy Gene Expression database linking published transcript and gene expression data to anatomical terms.
• Open-Source and FAIR Principles: Built on open-source principles and adheres to FAIR (Findable, Accessible, Interoperable, Reproducible) guidelines, supporting ongoing curation and versioning.

Scientific Applications:

• Anatomical Annotation: Standardizes vocabulary for annotation and organization of planarian anatomical data for S. mediterranea.
• Gene Expression Mapping: Enables linking of published transcript and gene expression data to specific anatomical terms via the Planarian Anatomy Gene Expression database.
• Developmental, Regeneration, and Evolutionary Studies: Facilitates comparative, developmental biology and regenerative medicine studies by providing interoperable anatomical terms across stages and body conditions.

Methodology:

Integration of terms from other established anatomy ontologies to achieve interoperability and support ontology-driven curation and database linking.