Plasmodium genome resources (PlasmoDB)

PlasmoDB provides integrated genomic and functional data for Plasmodium species through the EuPathDB Bioinformatics Resource Center (BRC) to support research on malaria biology.

Key Features:

• Annotated Genomes: Comprehensive genome annotations for multiple Plasmodium species at gene-specific and genome-wide scales.
• Transcription Evidence: Curated transcriptional evidence across parasite life-cycle stages supporting gene expression analyses.
• Proteomics Data: Proteomic datasets supporting protein identification and quantification.
• Functional Annotations: Functional annotations derived from experimental evidence to aid gene function inference.
• Population Biology and Evolution: Population biology and evolutionary datasets capturing genetic diversity and adaptation in Plasmodium populations.

Scientific Applications:

• Genomic Research: Supports gene- and genome-scale investigations of Plasmodium genetics.
• Functional Genomics: Enables integration of transcription, proteomics, and annotation data to link genes to function.
• Proteomics Studies: Facilitates protein identification, quantification, and downstream functional inference.
• Evolutionary Biology: Supports population genetics and evolutionary analyses of Plasmodium diversity and adaptation.
• Malaria Pathogenesis and Therapeutics: Informs molecular studies of malaria pathogenesis and potential therapeutic strategies.

Methodology:

Queries can be combined to integrate diverse datasets and enable gene-specific and genome-wide analyses.