PLncDB V2.0

PLncDB V2.0 provides a comprehensive repository of plant long noncoding RNAs (lncRNAs), integrating sequences, annotations, expression and regulatory information to support comparative and functional studies.


Key Features:

  • Extensive Data Collection: Contains over 1,246,372 lncRNAs derived from 13,834 RNA-Seq datasets across 80 plant species and integrates entries from EVLncRNAs and RNAcentral.
  • Uniform Annotation Pipeline: Applies a standardized annotation pipeline to produce consistent lncRNA annotations across species and datasets.
  • Visualization Tools: Includes JBrowse, eFP Browser, and EPexplorer for visualization of expression patterns and epigenetic signals.
  • Functional Exploration: Provides information on potential targets and regulatory networks associated with lncRNAs to support functional inference.

Scientific Applications:

  • Data Mining: Enables mining of large-scale lncRNA datasets to identify novel lncRNAs and survey known lncRNAs across species.
  • Functional Genomics: Supports analysis of lncRNA expression patterns and predicted regulatory relationships to infer functional roles.
  • Comparative Studies: Facilitates comparative analyses of lncRNA presence, expression and regulatory features among plant species.

Methodology:

Integration of lncRNA entries from EVLncRNAs and RNAcentral and processing of 13,834 RNA-Seq datasets using a standardized annotation pipeline.

Topics

Details

Added:
1/18/2021
Last Updated:
11/24/2024

Operations

Publications

Jin J, Lu P, Xu Y, Li Z, Yu S, Liu J, Wang H, Chua N, Cao P. PLncDB V2.0: a comprehensive encyclopedia of plant long noncoding RNAs. Nucleic Acids Research. 2020;49(D1):D1489-D1495. doi:10.1093/nar/gkaa910. PMID:33079992. PMCID:PMC7778960.

PMID: 33079992
PMCID: PMC7778960
Funding: - Zhengzhou Tobacco Research Institute: 110201601033(JY-07), 110201901024(SJ-03), 110202001020(JY-03) - China Association for Science and Technology: 2016QNRC001 - National Research Foundation of Singapore: NRF-RSSS-002