POInTsubbrowse sub

POInTsubbrowse sub facilitates orthology prediction and synteny exploration for paleopolyploid genomes using the Polyploidy Orthology Inference Tool (POInT) to infer orthologous relationships and provide confidence estimates across genomes affected by ancient polyploidy events.

Key Features:

• Conserved synteny and phylogenetic models: Uses conserved synteny and phylogenetic models to infer orthologous relationships among genomes sharing a common polyploidy event.
• Confidence estimates: Provides confidence estimates for orthology inferences produced by POInT.
• Polyploidy event coverage: Supports batch analysis across 12 distinct polyploidy events.
• Data export: Enables downloading of gene trees and coding sequences for orthologous genes meeting user-defined criteria.
• Curated orthology dataset: Provides access to a curated dataset of orthology inferences generated by POInT.

Scientific Applications:

• Evolutionary biology: Enables analysis of the genetic consequences of ancient polyploidy for studies of genome evolution.
• Species adaptation: Supports investigation of gene retention and loss patterns relevant to species adaptation.
• Functional genomics: Facilitates comparative functional inference by supplying orthologous gene sets and coding sequences.

Methodology:

Employs conserved synteny and phylogenetic models via the Polyploidy Orthology Inference Tool (POInT) to infer orthologous relationships and provide confidence estimates.