preprocessCore
preprocessCore provides core preprocessing routines in R within the Bioconductor ecosystem to perform normalization, filtering, and transformation of high-throughput genomic and molecular biology data for downstream statistical and bioinformatic analysis.
Key Features:
- Bioconductor integration: Implemented as a library within Bioconductor to enable cohesive workflows with other Bioconductor packages.
- R implementation: Uses the statistical programming language R to implement preprocessing routines.
- Core preprocessing operations: Provides normalization, filtering, and transformation routines for raw high-throughput genomic and molecular biology data.
- Statistical foundations: Applies preprocessing methods grounded in robust statistical principles.
- Efficiency and scalability: Implements routines intended to be efficient and scalable for high-throughput datasets.
- Quality control of packages: Packages undergo initial review and continuous automated testing to maintain quality and reliability.
- Interoperability: Produces interoperable packages to facilitate interdisciplinary analysis and integration with other bioinformatic tools.
Scientific Applications:
- Preprocessing of genomic data: Prepares high-throughput genomic and molecular biology data for downstream statistical and bioinformatic analysis.
- Data quality and consistency: Performs normalization, filtering, and transformation to ensure data quality and consistency across experimental conditions.
Methodology:
Implements preprocessing routines in R that perform normalization, filtering, and transformation grounded in robust statistical principles.
Topics
Collections
Details
- License:
- GPL-2.0
- Tool Type:
- command-line tool, library
- Operating Systems:
- Linux, Windows, Mac
- Programming Languages:
- R
- Added:
- 1/17/2017
- Last Updated:
- 11/25/2024
Operations
Publications
Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M. Orchestrating high-throughput genomic analysis with Bioconductor. Nature Methods. 2015;12(2):115-121. doi:10.1038/nmeth.3252. PMID:25633503. PMCID:PMC4509590.