PretoxTM

PretoxTM extracts treatment-related findings from preclinical toxicology reports using fine-tuned models trained on the PretoxTM dataset.

Key Features:

• PretoxTM Corpus: A gold standard corpus of preclinical treatment-related findings annotated by toxicology experts.
• PretoxTM Pipeline: Extracts treatment-related findings from preclinical study reports.
• PretoxTM Web App: Presents extracted information for expert visualisation and validation.

Scientific Applications:

• Preclinical toxicology analysis: Identifies adverse events in animal models during preclinical testing.
• Safety evaluation enhancement: Supports toxicology research and drug development decision-making by systematically extracting treatment-related findings from unstructured text.

Methodology:

The system uses models fine-tuned on the PretoxTM dataset to detect, extract, organise and visualise treatment-related findings from toxicology reports.