Privateer

Privateer validates and refines glycan three-dimensional structures to support structural biology and glycobiology analyses of carbohydrate ligands and protein glycosylation.

Key Features:

• 3D Structure Validation: Performs validation of glycan three-dimensional structures to detect modelling errors and support accurate representation for research and database deposition.
• Analysis and Refinement: Provides analysis and model-refinement capabilities for carbohydrate ligands to improve structural accuracy and reliability.
• Graphical Representation: Generates detailed graphical depictions of glycan spatial configurations and their interactions with proteins.

Scientific Applications:

• Structural Biology: Supports validation and refinement of carbohydrate ligands in macromolecular structures to improve interpretation of protein–carbohydrate interactions.
• Glycobiology: Enables analysis of glycan structures and conformations relevant to studies of protein glycosylation and carbohydrate function.
• Biological processes and disease mechanism studies: Assists investigations into carbohydrate–protein interactions that impact biological processes and disease mechanisms.

Methodology:

Combines computational validation, analysis, model refinement, and graphical representation of glycan structures in a unified workflow.