Probe and Primer Search

Probe and Primer Search generates comprehensive tables of probe and primer hits to identify and catalogue candidate probes and primers for genetic and immunogenetics analyses.

Key Features:

• Probe and primer hit table generation: Produces comprehensive tables of probe and primer hits for downstream analysis and selection.
• Integration with IPD: Integrates with the Immuno Polymorphism Database (IPD) to access polymorphic gene data related to immune system genes across multiple species.
• MHC-focused curation: Facilitates curation and publication of locus-specific databases with emphasis on the Major Histocompatibility Complex (MHC).
• Collaboration with nomenclature groups: Developed in collaboration with specialist groups and nomenclature committees to support accurate data curation and submission for online publication.
• Core database support: Uses five core databases, with the IMGT/HLA Database as the primary resource providing extensive information on human leukocyte antigen (HLA) genes.

Scientific Applications:

• Next Generation Sequencing workflows: Supports probe and primer selection and reporting for applications involving Next Generation Sequencing.
• MHC and immunogenetics research: Enables identification and cataloguing of probes and primers relevant to MHC-focused immunogenetics studies.
• Sequence dissemination: Supports dissemination of new and confirmatory sequences to the immunogenetics community and broader research and clinical fields.

Methodology:

Generates tables of probe and primer hits and integrates those results with the Immuno Polymorphism Database (IPD) and five core databases including the IMGT/HLA Database.