ProbResist

ProbResist catalogs experimentally supported reports of antibiotic resistance in probiotic bacteria to enable retrieval and analysis of resistant determinants, implicated antibiotics, and study provenance.

Key Features:

• Manually Curated Data: Built on manually curated reports to ensure accuracy of antibiotic resistance annotations in probiotic bacteria.
• Search Functionality: Targeted searches by bacterial names, antibiotics, or geographic locations allow focused retrieval of relevant records.
• Comprehensive Data Presentation: Results are available as a downloadable table including the antibiotic involved, probiotic species, resistant determinants, study location, PubMed Identifier and Digital Object Identifier.
• Analytical Tools: Simple analytical tools support interpretation and analysis of resistance trends and patterns within the database.

Scientific Applications:

• Research on Antibiotic Resistance: Resource for microbiologists studying mechanisms and determinants of antibiotic resistance in probiotic bacteria.
• Public Health Policy Development: Provides data to inform policy strategies addressing the spread of drug-resistant bacteria.
• Clinical Decision-Making: Supports evidence-based consideration of probiotic and antibiotic use by highlighting potential resistance issues.

Methodology:

Systematic collection and manual curation of published reports documenting antibiotic resistance in probiotic bacteria, with each database entry supported by experimental evidence.