Profeel

Profeel provides visualization and quantitative analysis of 1D, 2D, and 3D radiotherapy dosimetry datasets to support dosimetry research and quality assurance.

Key Features:

• Implementation: Implemented in MATLAB® (MathWorks Inc., MA).
• Dimensionality support: Handles import and processing of 1D, 2D, and 3D dosimetric datasets, including volumetric dose distributions.
• Gamma analysis: Performs gamma analysis for dose comparison.
• Normalization and filtering: Performs data normalization and filtering operations.
• Profile and PDD analysis: Provides automatic one-dimensional profile and percentage depth dose (PDD) analysis in accordance with International Electrotechnical Commission (IEC) standards.
• Measured vs simulated comparison: Supports quantitative comparison and discrepancy analysis between simulated and measured dosimetric data.
• Dimensionality extraction: Extracts lower-dimensionality data (profiles and dose planes) from volumetric doses.
• Custom functions: Allows creation and integration of user-defined custom analysis functions.
• Visualization: Enables visualization of dosimetric datasets and discrepancies across dimensions.

Scientific Applications:

• Radiotherapy quality assurance: Supports routine QA analyses such as gamma analysis and PDD verification.
• Dosimetry research: Enables quantitative assessment and comparison of measured and simulated dose distributions for research studies.
• Clinical dosimetry and practice: Provides profile and depth-dose analyses aligned with IEC standards to inform clinical dosimetry workflows.

Methodology:

Implemented in MATLAB®, Profeel performs gamma analysis, data normalization and filtering, automatic 1D profile and percentage depth dose (PDD) calculations per International Electrotechnical Commission (IEC) standards, extraction of lower-dimensionality data from volumetric doses, and quantitative comparisons between measured and simulated datasets while supporting user-defined custom functions.