Prokaryote RNA sequence analysis workflow

Prokaryote RNA sequence analysis workflow analyzes differential gene expression between two prokaryotic transcriptome datasets generated by next-generation DNA sequencing technologies.


Key Features:

  • Differential gene expression analysis: Compares two prokaryotic transcriptome datasets to identify differentially expressed genes.
  • Next-generation sequencing data support: Processes transcriptome data produced by next-generation DNA sequencing technologies.
  • Automated provenance tracking: Records computational steps, inputs, and outputs to support reproducibility.
  • Sophisticated statistical methods: Applies advanced statistical techniques for differential expression analysis.
  • Scalability: Handles large-scale prokaryotic RNA-seq datasets.

Scientific Applications:

  • Differential expression studies: Identify genes with altered expression between two prokaryotic transcriptome datasets.
  • Comparative prokaryotic transcriptomics: Compare transcriptomes to investigate transcriptional differences between samples.
  • Large-scale transcriptome analysis: Characterize global transcriptional patterns from high-throughput sequencing data in prokaryotes.

Methodology:

An automated workflow with provenance tracking that applies statistical methods for differential gene expression analysis on NGS-derived prokaryotic transcriptome datasets.

Topics

Details

Tool Type:
workflow
Operating Systems:
Linux, Windows, Mac
Added:
5/21/2015
Last Updated:
12/10/2018

Operations

Publications

Afgan E, Baker D, van den Beek M, Blankenberg D, Bouvier D, Čech M, Chilton J, Clements D, Coraor N, Eberhard C, Grüning B, Guerler A, Hillman-Jackson J, Von Kuster G, Rasche E, Soranzo N, Turaga N, Taylor J, Nekrutenko A, Goecks J. The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2016 update. Nucleic Acids Research. 2016;44(W1):W3-W10. doi:10.1093/nar/gkw343. PMID:27137889. PMCID:PMC4987906.