promor
promor performs label-free quantification proteomics data analysis and builds machine-learning-based predictive models to prioritize top protein candidates.
Key Features:
- R package: Implemented in R for computational proteomics analyses.
- Label-free quantification: Performs label-free quantification of proteins directly from mass spectrometry data.
- Predictive modeling: Incorporates machine learning methodologies to build predictive models for protein candidate ranking.
- High-throughput analysis: Supports workflows applicable to high-throughput proteomic studies.
Scientific Applications:
- Biomarker discovery: Prioritizes protein candidates for identification of biomarkers in biological processes and disease mechanisms.
- Proteome quantification: Enables quantitative analysis of proteomes using label-free mass spectrometry data.
- Predictive proteomics: Produces predictive models from proteomics datasets to assess protein relevance.
Methodology:
Performs label-free quantification from mass spectrometry data and applies machine-learning-based predictive modeling.
Topics
Details
- License:
- LGPL-2.1
- Cost:
- Free of charge
- Tool Type:
- library
- Operating Systems:
- Mac, Linux, Windows
- Programming Languages:
- R
- Added:
- 3/23/2023
- Last Updated:
- 11/24/2024
Operations
Publications
Ranathunge C, Patel SS, Pinky L, Correll VL, Chen S, Semmes OJ, Armstrong RK, Combs CD, Nyalwidhe JO. promor: a comprehensive R package for label-free proteomics data analysis and predictive modeling. Bioinformatics Advances. 2023;3(1). doi:10.1093/bioadv/vbad025. PMID:36922981. PMCID:PMC10010602.