promor

promor performs label-free quantification proteomics data analysis and builds machine-learning-based predictive models to prioritize top protein candidates.


Key Features:

  • R package: Implemented in R for computational proteomics analyses.
  • Label-free quantification: Performs label-free quantification of proteins directly from mass spectrometry data.
  • Predictive modeling: Incorporates machine learning methodologies to build predictive models for protein candidate ranking.
  • High-throughput analysis: Supports workflows applicable to high-throughput proteomic studies.

Scientific Applications:

  • Biomarker discovery: Prioritizes protein candidates for identification of biomarkers in biological processes and disease mechanisms.
  • Proteome quantification: Enables quantitative analysis of proteomes using label-free mass spectrometry data.
  • Predictive proteomics: Produces predictive models from proteomics datasets to assess protein relevance.

Methodology:

Performs label-free quantification from mass spectrometry data and applies machine-learning-based predictive modeling.

Topics

Details

License:
LGPL-2.1
Cost:
Free of charge
Tool Type:
library
Operating Systems:
Mac, Linux, Windows
Programming Languages:
R
Added:
3/23/2023
Last Updated:
11/24/2024

Operations

Publications

Ranathunge C, Patel SS, Pinky L, Correll VL, Chen S, Semmes OJ, Armstrong RK, Combs CD, Nyalwidhe JO. promor: a comprehensive R package for label-free proteomics data analysis and predictive modeling. Bioinformatics Advances. 2023;3(1). doi:10.1093/bioadv/vbad025. PMID:36922981. PMCID:PMC10010602.

Documentation

Links