ProSeqViewer

ProSeqViewer provides TypeScript-based visualization of single-nucleotide and amino-acid sequences and their annotations to support sequence alignment, comparison, and functional site mapping.

Key Features:

• Interactive Visualization: Visualizes single-nucleotide and amino-acid sequences alongside multiple sequence alignments and supports interactive exploration.
• Alignment and Annotation Mapping: Supports visualization of sequence alignments, sequence comparison, and annotation mapping including functional domains, binding sites, and modification sites.
• Modular Architecture: Modular architecture enables integration as a component within larger bioinformatics platforms and pipelines.
• Implementation and Output: Implemented in TypeScript and generates pure HTML output for compatibility with standard web formats.
• Event Exchange: Exposes event exchange mechanisms to communicate with other visualization components and bioinformatics workflows or databases.

Scientific Applications:

• Sequence Alignment and Comparison: Facilitates alignment visualization and comparative analysis across evolutionary-related sequences.
• Functional Domain Mapping: Enables identification and mapping of functional domains within protein sequences.
• Site Identification: Enables pinpointing of binding sites and modification sites within sequences.

Methodology:

Implemented as a TypeScript library that leverages modern web technologies and produces HTML output.