Proteosign

Proteosign automates statistical evaluation of differential protein expression from large-scale mass spectrometry (MS) data to identify proteins with significant abundance changes.


Key Features:

  • Automated Analysis Pipeline: Performs automated statistical evaluation of differential protein expression from MS-derived quantitative data.
  • Advanced Statistical Methods: Applies advanced statistical methods for robust and reliable identification of differentially expressed proteins.
  • Publication-Quality Visualization: Produces high-quality plots for presenting differential expression results.
  • Large-Scale MS Data Support: Handles large-scale mass spectrometry (MS) datasets for proteomic analyses.

Scientific Applications:

  • Differential Protein Expression Analysis: Enables analysis of proteome dynamics in studies of disease mechanisms, cellular signaling pathways, and biomarker discovery.

Methodology:

Automated statistical evaluation using advanced statistical methods to identify differentially expressed proteins from large-scale MS data and generate publication-quality plots.

Topics

Collections

Details

Tool Type:
web application
Operating Systems:
Linux, Windows, Mac
Programming Languages:
JavaScript, PHP, R
Added:
9/19/2017
Last Updated:
11/25/2024

Operations

Publications

Efstathiou G, Antonakis AN, Pavlopoulos GA, Theodosiou T, Divanach P, Trudgian DC, Thomas B, Papanikolaou N, Aivaliotis M, Acuto O, Iliopoulos I. ProteoSign: an end-user online differential proteomics statistical analysis platform. Nucleic Acids Research. 2017;45(W1):W300-W306. doi:10.1093/nar/gkx444. PMID:28520987. PMCID:PMC5793730.

Documentation

Links