Proteosign
Proteosign automates statistical evaluation of differential protein expression from large-scale mass spectrometry (MS) data to identify proteins with significant abundance changes.
Key Features:
- Automated Analysis Pipeline: Performs automated statistical evaluation of differential protein expression from MS-derived quantitative data.
- Advanced Statistical Methods: Applies advanced statistical methods for robust and reliable identification of differentially expressed proteins.
- Publication-Quality Visualization: Produces high-quality plots for presenting differential expression results.
- Large-Scale MS Data Support: Handles large-scale mass spectrometry (MS) datasets for proteomic analyses.
Scientific Applications:
- Differential Protein Expression Analysis: Enables analysis of proteome dynamics in studies of disease mechanisms, cellular signaling pathways, and biomarker discovery.
Methodology:
Automated statistical evaluation using advanced statistical methods to identify differentially expressed proteins from large-scale MS data and generate publication-quality plots.
Topics
Collections
Details
- Tool Type:
- web application
- Operating Systems:
- Linux, Windows, Mac
- Programming Languages:
- JavaScript, PHP, R
- Added:
- 9/19/2017
- Last Updated:
- 11/25/2024
Operations
Publications
Efstathiou G, Antonakis AN, Pavlopoulos GA, Theodosiou T, Divanach P, Trudgian DC, Thomas B, Papanikolaou N, Aivaliotis M, Acuto O, Iliopoulos I. ProteoSign: an end-user online differential proteomics statistical analysis platform. Nucleic Acids Research. 2017;45(W1):W300-W306. doi:10.1093/nar/gkx444. PMID:28520987. PMCID:PMC5793730.
Documentation
Links
Repository
https://github.com/yorgodillo/ProteoSign