Protist Guru

Protist Guru integrates visualization and analysis of gene expression data from 15 protist species to investigate molecular functions and pathways in microbial eukaryotes.

Key Features:

• Functional Co-expression Networks: Identification and analysis of functional co-expression networks among protist genes to infer gene interactions and cellular functions.
• Gene Family Identification: Detection of gene families to explore evolutionary relationships and functional similarities across protist species.
• Enriched Gene Cluster Analysis: Analysis of enriched gene clusters to pinpoint genes involved in specific biological pathways or processes, including secondary carotenoid biosynthesis in Haematococcus lacustris.
• Multi-species Gene Expression Compendium: Curated gene expression data assembled from 15 distinct protist species with associated sample annotations.
• Visualization and Analysis of Expression Data: Tools for visualizing and analyzing gene expression profiles and network relationships within and across protist species.

Scientific Applications:

• Pathway Elucidation: Reveals genes and co-expression modules involved in biochemical and physiological pathways in protists.
• Microbial Ecology Insights: Links gene expression patterns to ecological functions of protists, informing studies of their roles in ecosystems.
• Discovery of Biosynthetic Processes: Facilitates identification of gene sets and networks underlying specific processes such as secondary carotenoid synthesis in Haematococcus lacustris.

Methodology:

The resource is built on curated gene expression data; co-expression networks were generated and sample annotations are provided.