Pse-in-One
Pse-in-One generates numerical feature vectors that encode sequence composition and physicochemical properties for DNA, RNA, and protein sequences to support computational analyses.
Key Features:
- Versatility Across Biological Sequences: Handles DNA, RNA, and protein sequences for unified feature extraction.
- Extensive Built-In Properties: Provides a comprehensive library of built-in physicochemical and sequence-derived properties for feature representation.
- Customizable Feature Vectors: Allows specification of user-defined properties to create tailored feature vectors.
- Multiple Modes of Generation: Implements 28 different modes for generating a wide range of feature vectors.
- Integration with Machine Learning Algorithms: Produces feature matrices compatible with machine-learning algorithms used in bioinformatics and systems biology tasks.
Scientific Applications:
- Computational Proteomics and Genomics: Supports studies of protein structure–function relationships and analysis of genomic variations.
- Biological Sequence Analysis: Enables comprehensive sequence characterization for molecular biology and comparative analyses.
Methodology:
Integrates multiple physicochemical and sequence-derived properties across 28 generation modes to produce numerical feature vectors for DNA, RNA, and protein sequences.
Topics
Details
- Tool Type:
- web application
- Operating Systems:
- Linux, Windows, Mac
- Added:
- 5/20/2018
- Last Updated:
- 12/10/2018
Operations
Publications
Liu B, Liu F, Wang X, Chen J, Fang L, Chou K. Pse-in-One: a web server for generating various modes of pseudo components of DNA, RNA, and protein sequences. Nucleic Acids Research. 2015;43(W1):W65-W71. doi:10.1093/nar/gkv458. PMID:25958395. PMCID:PMC4489303.