Pse-in-One

Pse-in-One generates numerical feature vectors that encode sequence composition and physicochemical properties for DNA, RNA, and protein sequences to support computational analyses.


Key Features:

  • Versatility Across Biological Sequences: Handles DNA, RNA, and protein sequences for unified feature extraction.
  • Extensive Built-In Properties: Provides a comprehensive library of built-in physicochemical and sequence-derived properties for feature representation.
  • Customizable Feature Vectors: Allows specification of user-defined properties to create tailored feature vectors.
  • Multiple Modes of Generation: Implements 28 different modes for generating a wide range of feature vectors.
  • Integration with Machine Learning Algorithms: Produces feature matrices compatible with machine-learning algorithms used in bioinformatics and systems biology tasks.

Scientific Applications:

  • Computational Proteomics and Genomics: Supports studies of protein structure–function relationships and analysis of genomic variations.
  • Biological Sequence Analysis: Enables comprehensive sequence characterization for molecular biology and comparative analyses.

Methodology:

Integrates multiple physicochemical and sequence-derived properties across 28 generation modes to produce numerical feature vectors for DNA, RNA, and protein sequences.

Topics

Details

Tool Type:
web application
Operating Systems:
Linux, Windows, Mac
Added:
5/20/2018
Last Updated:
12/10/2018

Operations

Publications

Liu B, Liu F, Wang X, Chen J, Fang L, Chou K. Pse-in-One: a web server for generating various modes of pseudo components of DNA, RNA, and protein sequences. Nucleic Acids Research. 2015;43(W1):W65-W71. doi:10.1093/nar/gkv458. PMID:25958395. PMCID:PMC4489303.

Documentation