PseudoChecker

PseudoChecker identifies disruptive mutations through comparative genomics to detect gene inactivation.


Key Features:

  • Automated Comparative Genomics Approach: Detects disruptive mutations indicative of gene inactivation using an automated comparative genomics methodology.

Scientific Applications:

  • Evolutionary Biology: Supports research on gene inactivation and evolutionary novelty across different species.

Methodology:

PseudoChecker employs comparative genomics to detect patterns of gene inactivation by identifying disruptive mutations.

Topics

Details

Added:
1/18/2021
Last Updated:
1/29/2021

Operations

Publications

Alves LQ, Ruivo R, Fonseca MM, Lopes-Marques M, Ribeiro P, Castro LFC. PseudoChecker: an integrated online platform for gene inactivation inference. Nucleic Acids Research. 2020;48(W1):W321-W331. doi:10.1093/nar/gkaa408. PMID:32449938. PMCID:PMC7319564.

Documentation