pseudoMap

pseudoMap maps sRNA sequencing data to transcribed pseudogenes (TPGs) to identify siRNA–target interactions and miRNA decoy relationships for studying post-transcriptional regulation.

Key Features:

• siRNA-Mediated Mechanisms: Focuses on TPGs that generate siRNAs to regulate protein-coding genes via the RNAi pathway.
• miRNA Decoy Functionality: Identifies TPGs acting as decoys for miRNAs that can affect parental gene expression.
• Integration with Deep Sequencing Data: Combines sRNA/deep sequencing data to map siRNA–target interactions.
• Comprehensive Annotations and Predictions: Provides annotations and predictions of siRNA–target interactions and miRNA decoy relationships.

Scientific Applications:

• Gene Silencing Mechanisms: Supports research on non-coding RNA in human cells to investigate post-transcriptional regulation and potential therapeutic strategies.

Methodology:

Maps TPGs to sRNAs using sRNA/deep sequencing data, maps siRNA–target interactions, and incorporates miRNA annotations to identify miRNA decoy relationships.