pSuc-EDBAM
pSuc-EDBAM predicts lysine succinylation sites in protein sequences by extracting and prioritizing features using ensemble dense blocks with an attention module and one-hot encoded 1-D CNN feature maps to support studies of protein function and disease pathways.
Key Features:
- Ensemble Dense Blocks and Attention Module: Captures intricate succinylation-related sequence patterns and prioritizes informative features.
- One-Hot Encoding and 1-D CNN: Converts protein sequences into one-hot representations and generates low-level feature maps via 1-D convolution.
- Multi-Layered Learning Strategy: Applies stacked ensemble dense-block learning for hierarchical feature extraction and representation.
Scientific Applications:
- Lysine Succinylation Research: Predicts potential lysine succinylation sites to aid investigations of protein function and disease pathways.
Methodology:
Represents sequences with one-hot encoding, produces feature maps using a 1-D CNN, and applies ensemble dense blocks with an attention module within a multi-layered learning strategy for feature extraction and prioritization.
Topics
Details
- Cost:
- Free of charge
- Tool Type:
- web application
- Operating Systems:
- Mac, Linux, Windows
- Added:
- 3/23/2023
- Last Updated:
- 11/24/2024
Operations
Data Inputs & Outputs
PTM site prediction
Publications
Jia J, Wu G, Li M, Qiu W. pSuc-EDBAM: Predicting lysine succinylation sites in proteins based on ensemble dense blocks and an attention module. BMC Bioinformatics. 2022;23(1). doi:10.1186/s12859-022-05001-5. PMID:36316638. PMCID:PMC9620660.