pSuc-EDBAM

pSuc-EDBAM predicts lysine succinylation sites in protein sequences by extracting and prioritizing features using ensemble dense blocks with an attention module and one-hot encoded 1-D CNN feature maps to support studies of protein function and disease pathways.


Key Features:

  • Ensemble Dense Blocks and Attention Module: Captures intricate succinylation-related sequence patterns and prioritizes informative features.
  • One-Hot Encoding and 1-D CNN: Converts protein sequences into one-hot representations and generates low-level feature maps via 1-D convolution.
  • Multi-Layered Learning Strategy: Applies stacked ensemble dense-block learning for hierarchical feature extraction and representation.

Scientific Applications:

  • Lysine Succinylation Research: Predicts potential lysine succinylation sites to aid investigations of protein function and disease pathways.

Methodology:

Represents sequences with one-hot encoding, produces feature maps using a 1-D CNN, and applies ensemble dense blocks with an attention module within a multi-layered learning strategy for feature extraction and prioritization.

Topics

Details

Cost:
Free of charge
Tool Type:
web application
Operating Systems:
Mac, Linux, Windows
Added:
3/23/2023
Last Updated:
11/24/2024

Operations

Data Inputs & Outputs

Publications

Jia J, Wu G, Li M, Qiu W. pSuc-EDBAM: Predicting lysine succinylation sites in proteins based on ensemble dense blocks and an attention module. BMC Bioinformatics. 2022;23(1). doi:10.1186/s12859-022-05001-5. PMID:36316638. PMCID:PMC9620660.

PMID: 36316638
PMCID: PMC9620660
Funding: - National Natural Science Foundation of China: 61761023, 62162032 - Natural Science Foundation of Jiangxi Province: 20202BABL202004