ptm

ptm analyzes post-translational modifications, focusing on methionine sulfoxidation, for scalable analysis of thousands of proteins.

Key Features:

• Database Integration: Integrates information from up to 11 databases covering nine different PTMs.
• Flexible Analysis Pipelines: Provides flexible analysis pipelines and a suite of functions for scalable processing of thousands of proteins.
• Simultaneous Multi-analysis: Supports simultaneous multi-analysis of multiple proteins and modifications.
• Cross-Modification Applicability: Analytical tools apply to PTMs beyond methionine sulfoxidation.
• Programmatic Analysis: Implements R functions for automated processing of large-scale proteomic data.

Scientific Applications:

• Methionine Sulfoxidation Analysis: Analyze methionine sulfoxidation to investigate its role in cell signaling.
• PTM Exploration: Explore other post-translational modifications using the same analytical framework.
• Hypothesis Testing: Formulate and test hypotheses about specific modification sites or whole proteins affected by PTMs.

Methodology:

Aggregating data from multiple databases and utilizing R functions for automated processing of large-scale proteomic data.