pyseer

PySEER: Microbial Genome-Wide Association Study Analysis

PySEER performs microbial genome-wide association studies (GWAS) by integrating statistical methods tailored to microbial population structure and pangenome variation.

Key Features:

• Microbial GWAS Framework: Implements association testing methods adapted to microbial genomes and population structures.
• Pangenome-Wide Analysis: Supports microbial pangenome-wide association studies to link genetic variation with phenotypic traits.
• Flexible Input Handling: Accepts diverse genomic data types for association analysis.
• Association Interpretation: Provides methods for interpreting and contextualizing association results.

Scientific Applications:

• Microbial Genetics: Identifies genetic determinants underlying microbial phenotypes and evolutionary traits.

Methodology:

Integrates multiple statistical techniques within a Python-based framework to model microbial genomic variation and population structure, enabling comprehensive association testing across core and accessory genomes.